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Due to a bomb scare at the General, the hospital is overrun with patients. New doctors are introduced. Phil Kirkby (played by Andrew Clover) is eager, but tries too hard to impress. Smedley (Peter O'Brien of Neighbours fame) is the new registrar, who impresses the other doctors with his knowledge. In the same episode, he saves a patient who has a collapsed lung. Dr. Collin is no longer a beginner and is now one of the experienced doctors. He is now married, and is often taking personal phone calls from his wife, Alison. The hospital manager Alex Legg (from series 1) makes a brief appearance, only to be killed off from a heart attack. Adrian DeVries (Jack Fortune) is the new consultant surgeon - he can perhaps be seen as this series' replacement for Mr. Betancourt. Incidentally, for the first time, the cameras move outside to show DeVries driving his car.
This episode features a patient who has prolonged hypothermia. Claire and Dr. Mortimer provide extended resus. During the long process, Dr. Mortimer reads from a sex novel. As a result of a managerial meeting, it is decided that junior doctors are expected to cover the specialist Ear, Nose and Throat cases, to the objection of Mr. Docherty who believes the plan is madness. He is proved right in episode 5. Alf Grocott, a terminally ill patient is introduced. He is told that he has lung cancer, however he tells Dr. Collin that he does not want his daughter told. Alf's daughter also tells Dr. Collin not to inform her father of the diagnosis.
In this powerful episode, the main storyline is that of Heather Parsons, a girl who brought in with flu, but later develops meningitis and dies. The blame for misdiagnosis is laid at the door of the blundering GP, Dr. Wilson, although it is Andrew to has to carry the can. Andrew takes some small revenge on Dr. Wilson by pretending to be a patient experiencing symptoms of diabetes, and then turning the tables when Wilson clearly fails to recognise them. Maitland starts to question whether or not she wants to be a doctor anymore. Nasreen, a police officer, and an old school friend of Raj is introduced
Kirkby becomes attracted to a woman who is brought in with a sickle cell crisis, however it turns out she is faking some of her symptoms in order to get a ""fix"" of painkillers. Caroline is suspended after a patient dies in suspicious cirumstances. Raj and Nasreen kiss and become lovers at the hospital ball. Maitland starts the night with a handsome helicopter pilot, however both he and DeVries are brushed aside at the end of the evening in favour of Smedley. Mr. Docherty is informed that one of his operating lists is no longer available.
The investigation continues in to the death of an elderly patient. Nurse Chandley is interrogated by the hospital manager Paul Tennant. Eventually Andrew finds out from a conversation with Alf Grocott that it is the patient's niece who was responsible. Alf is sent home. Dr. Turner, Dr. Yates and Tennant agree to cover up the death of a second patient.
A film crew arrives at the hospital to make a promotional video. The director of the crew (played by none other than Game On's Neil Stuke) is revealed to be the boyfriend of Dr. Mortimer. Mr. Docherty is under pressure from Mr. Tennant to retire. Maitland reports her experiences to the papers. In a meeting with Tennant, he explains that she cannot be suspended for this, however she is suspended for failing to pay for a pint of milk from the canteen. Maitland decides to dump Smedley by telling him he has the smallest dick she's ever seen. Smedley goes out driving and overturns his car in an accident. Raj has a bit of fun with a man who is suffering from complete amnesia. At the end of the episode, Maitland cries her heart out in the arms of Mr. Cullen's widow
Dr. Mortimer is diagnosed with AIDS. His diagnosis is leaked, and the hospital manager Tennant tried to convince him to take a leave of absence, but he refuses. DeVries gets some blood from Sister Pereira's child whom he believes is his son. Alf Grocott is re-admitted to the hospital, and is told that the cancer has spread to his liver. He dies on Christmas day. Dr. Collin starts an affair with Caroline. Kirkby draws up chemotheraphy wrongly. He seeks advice from Dr. Turner, although is told to carry on even though he doesn't know what to do. The patient suffers from a reaction and dies.
The teenage daughter of Sister Landers is brought in with an abcess. When trouble develops during her operation to remove it, Mortimer steps in. Maitland gets back together with DeVries. Dr. Turner and Paul Tennant try to persuade Kirkby to lie at the inquest. In return they promise to look out for him in the future and provide him with the best work and references. The inquest returns a verdict of unlawful killing, and a possible manslaughter charge to follow. Maitland decides to return to the hospital after coming to the aid of man who has a heart attack while she is having a job interview
