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Mel and her dishonourable assistant Lou Sanders are joined by brilliant stand-ups Sarah Millican, Jamali Maddix and Chris McCausland. Sarah discusses what ingredient she thinks should be added to cakes in Amsterdam, Chris has to apologise to one of the victims of his prank-fuelled past while Jamali and Mel find out they have similar tactics when being caught short without a loo.
Mel and Lou are joined by the brilliant Katherine Ryan, Drag Race standout star Bimini Bon Boulash, and stand-up Toussaint Douglass. Katherine spills the beans on her prom night, Bimini reveals what happens after too many vodkas and Toussaint explains why you should never accept chicken from strangers.
Mel and Lou are joined by stand-up and Strictly champion Bill Bailey, award-winning comedian Rosie Jones and former heavyweight champion of the world David Haye. Bill comes face to face with multiple victims of his and his dog's bad behaviour, David overshares about creative ways to take his training supplements and Rosie confesses all the times she's used her disability for evil.
Mel and Lou are joined by the hilarious Rob Beckett, Scarlett Moffatt, and Paul Chowdhry. Rob dishes the dirt about a date that went wrong, Scarlett reveals what happens when you take her on a girls holiday and Paul tells us why gigging isn't always a laugh.
Mel and Lou are joined by actor Sally Phillips, comedian Alan Davies and stand-up Ria Lina. Sally reveals the best way to get back at a horrible boss, Alan tells all about his court appearance and we find out why you should never leave your kids with Ria.
Mel and Lou are joined by radio DJ Sara Cox, TV favourite Keith Lemon and Britain's Got Talent's Nabil Abdulrashid. Sara faces the consequences of her less than model behaviour, Keith overshares about puberty and Nabil is confronted by the many victims of his pranks.
Mel and Lou are joined by the brilliant Jack Dee, TV sweetheart Lorraine Kelly, and internet sensation Munya Chawawa. Jack tells all about an unintentional rock and roll night on tour, we find out how Lorraine talks to her bosses and Munya is confronted by the victim of a prank that went too far.
Mel and Lou are joined by comedian Jason Manford, Strictly star AJ Odudu and actor Jessica Knappett. Jason reveals the lengths he'd go to not share a room with his brother, AJ reveals the secret to DJing, and Jessica explains why you should never attend a funeral with her.
